항바이러스 약물(항바이러스 제/항바이러스 물질), Antiviral drugs(Antiviral agents)

herpesvirus encephalitis

oral

2 years old or older

3200mg/

80mg per kg of body weight as a daily supply, dividing the daily supply into 4 divide doses for 5 days, the maximum amount per day is 3200mg/day

30 mg per kg of body weight as a daily supply for 7 to 10 days, or 1500 mg/m2 per day in 3 minutes for 7 to 10 days, some experts treat 30 mg per kg of body weight as a daily supply

Chickenpox in children with immune-competent conditions

30mg per kg of body weight per day for 7-10 days in 3 divided doses 1500mg/m per day for 1 year old or over 1 year old 22Maximum dose is divided into 3 parts for 7-10 days

shingles in an immune-competent state

All age

Same as chickenpox treatment for children with immune-compromising status. However, if you are 12 years old or over 12 years old, take 4000 mg per day in 5 minutes for 5-7 days.

under 12=-years old

Herpesvirus infection (locally, progressively, disseminated) in children with immune-compromising conditions

30mg per kg of body weight per day for 7-14 days in 3 minutes, 15 mg per day for 3 minutes 7-14 days for 12 years old or over 12 years old, or 1000mg per day for 3-5 minutes for 2 years or older 7- 14 days

Prevention of herpesvirus infection in children with compromised immune systems

Oral

2 yeas -ols or older

600-1000mg per day for 3-5 minutes during the period of risk of infection

Herpesvirus seropositive

Oral

15 mg/kg per day for 3 minutes during the period of risk of infection

Genital herpesvirus infection, if first

Oral

12 years old or older

1000-1200mg/kg per day in 3-5 divided doses for 7-10 days or Light pediatric dose-1 day 40-80mg/kg in 3-4 divided doses for 5-10 days (the maximum daily dose is 1gm/kg)

Genital herpesvirus infection, if first

Oral

12 years old or older

1000-1200 mg/kg per day in 3-5 divisions for 7-10 days, or light pediatric dose – 40-80 mg/kg per day in 3-4 divisions for 5-10 days (the highest daily dose is 1 gm/kg) or intravenous injection For children 12 years of age or older, 15 mg/kg of body weight per day in 3 divided doses for 5-7 days

12 years old or older

Oral

1 800-1200 mg/kg in 2 minutes for 12 months

chronic hepatitis B

Oral

18 years old or older

10 mg once a day, 1 to 3 years, the most appropriate treatment period is still unknown

Oral

1-9 yeas-old

For treatment and prophylaxis, 5 mg/Kg per day for 2 minutes, the maximum dose is 150 mg per day

Oral

10 years old or older

For treatment and prophylaxis, if you weigh less than 40 kg, take 5 mg/Kg per day for 2 divide dose

Oral

Dosage is calculated by body weight, not by age

For prevention purposes, for children and adults weighing 20 kg or more, 100 mg per day

cytomegalovirus retinitis

adult

Initial genital herpesvirus infection

Oral

adult

Oral

adult

250 mg per day in 2 divided doses for 3-5 days

Oral

adult

intra orbital

adult

330 micrograms are injected into the vitreous. The first 2 doses are given every 2 weeks, and then every 4 weeks thereafter.

cytomegalovirus retinitis in people with HIV infection syndrome

adult

180mg/kg per day for 2 minutes and treated for 14-20 days, then 90-120mg once a day maintenance treatment.

When herpesvirus infection in immunocompromised individuals is resistant to Acyclovir treatment

adult

80~120mg/kg per day is divided into 2~3 doses and treated until the infectious disease is completely healed.

adult

10 mg/kg per day in 2 minutes and treated for 14 to 20 days. For long-term suppressive treatment, 5 mg/kg per day is treated for 7 days, and 6 mg/kg per day is treated for 5 days per week.

To prevent cytomegalovirus infection in people at high risk

adult

10 mg/kg per day for 2 minutes and treatment for 1 week, then 5 mg/kg per day for 7 days, and 6 mg/kg per day for 5 days per week.

Oral

adult

1 gm 3 times a day treatment.

Hepatitis B chronic hepatitis

Oral

2 years old or older

(HIV와 B형 간염이 동시에 있는 아이 경우는 HIV 치료에 해당되는 용량으로 치료한다)

3mg/Kg per day (maximum daily dose of 100mg) (Children who have both HIV and hepatitis B should be treated with the appropriate dose for HIV treatment) 

Oral

1-12-year-old

It is used to treat children 1-12 years old. For prevention, once a day, for treatment, 30 mg for those under 15 kg, twice a day, 45 mg twice a day for 15-23 kg, 45 mg twice a day for 23-40 kg, 75 mg twice a day for people over 40 kg Twice a day

Prevention and treatment of influenza A and influenza B

Oral

13 years old or older

75 mg twice a day for treatment, once a day for prevention

6gm spray treatment for 18 hours a day for 3 to 7 days, or 3 times for 2 hours a day, or other appropriate treatment.

Dosage is determined according to body weight

200mg in the morning and evening for 25-30kg, 200mg in the morning and 400mg in the evening for 36-49kg, 400mg in the morning and evening for 49-61kg, 400mg in the morning for 600mg in the morning, 600mg in the evening for more than 75kg 600mg in the morning 600mg in the evening

oral/ liquid

3 years old or older

Influenza A treatment

Oral

13 years old or older

200mg per day in 2 divided doses

Oral

1 years old or older

For children 1 to 9 years old, 5 mg once a day (maximum dose is 150 mg once a day)

Influenza A prophylactic treatment

Oral

10 years old or older

For those weighing 40 kg or less, take 5 mg/kg per day in 2 minutes, and for those weighing 40 kg or more, take 200 mg per day in 2 minutes

Oral

2 gm per day in 2 minutes for 10 days

Oral

1 gm per day for 2 minutes for 3 days

Daily suppression genital herpesvirus infection treatment

Oral

Use 500-1000 mg per day for 1 year and then reevaluate.

Influenza A and Influenza B treatment

7 years-old or older

Use 10 mg per day for 5 days and it is not yet recommended for prophylactic treatment.

Reviewed 3/2015

Copyright ⓒ 2015 John Sangwon Lee, MD., FAAP

미국 소아과 전문의, 한국 소아청소년과 전문의 이상원 저 “부모도 반의사가 되어야 한다”-내용은 여러분들의 의사로부터 얻은 정보와 진료를 대신할 수 없습니다.

The information contained in this publication should not be used as a substitute for the medical care and advice of your doctor. There may be variations in treatment that your doctor may recommend based on individual facts and circumstances. “Parental education is the best medicine.”